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BASELINE AND INTERFERON‐ENHANCED NATURAL KILLER CELL ACTIVITY IN RHEUMATOID ARTHRITIS
Author(s) -
PEDERSEN BENTE K.,
BEYER JANNIE M.,
KLARLUND KIM,
CLEMMENSEN INGE H.
Publication year - 1985
Publication title -
acta pathologica microbiologica scandinavica series c: immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0202
DOI - 10.1111/j.1699-0463.1985.tb02926.x
Subject(s) - rheumatoid arthritis , baseline (sea) , medicine , interferon , immunology , biology , fishery
Natural killer (NK) cell activity against the leukemia cell line K‐562 was tested in 45 patients with rheumatoid arthritis (RA) who either had not received any remission‐inducing drugs for more than 6 months or had received penicillamine for at least 6 months. Baseline NK cell activity and interferon (IF)‐enhanced NK cell activity did not differ from that observed in 45 controls matched for age and sex, and neither NSAID (non steroidal anti‐inflammatory drugs) nor penicillamine influenced NK cell activity. There was no correlation between NK cell activity and acute‐phase reactants.