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Hydrophobized Wound Dressing in the Treatment of Experimental Staphylococcus Aureus Infections in the Young Pig
Author(s) -
Wadström Torkel,
Björnberg Sten,
Hjertén Stellan
Publication year - 1985
Publication title -
acta pathologica microbiologica scandinavica series b: microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0180
DOI - 10.1111/j.1699-0463.1985.tb02901.x
Subject(s) - staphylococcus aureus , microbiology and biotechnology , medicine , biology , bacteria , genetics
Standard wounds (2times2 cm) produced with a dermatome, followed by a thermal injury in four‐week‐old piglets were inoculated with Staphylococcus aureus strains. Infection developed in each wound within a few days. Wounds were then dressed separately with cellulose dressing or the same dressing substituted with a hydrophobic ligand (stearylic acid). Other wounds were treated with active charcoal dressing (Actisorb R ) or Debrisan R. Signs of healing, including vanishing of inflammation around the wounds, were noticed already on days 3 and 4 in the wounds treated with the hydrophobized dressing, and no infection was noticed in such wounds on days 5 to 6, while all other wounds were still showing signs of infection. It is concluded that active removal of S. aureus cells in the hydrophobized dressing probably decreases the number of multiplying bacteria in wounds, causing a rapid onset of wound healing.