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DNA FLOW CYTOMETRY IN PRIMARY BREAST CARCINOMA
Author(s) -
FOSSÅ S. D.,
THORUD E.,
SHOAIB M. C.,
PETTERSEN E. O.,
HØIE J.,
KNUDSEN O. SCOTT
Publication year - 1984
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1984.tb04430.x
Subject(s) - flow cytometry , breast carcinoma , dna , primary (astronomy) , medicine , cancer research , biology , breast cancer , immunology , genetics , cancer , physics , astronomy
DNA Flow cytometric values were recorded in 66 primary breast carcinomas. Twenty‐six tumors were found to be diploid whereas 40 were non‐diploid. About 10% of the cells belonged to the S‐phase fraction. Non‐diploid tumors had significantly larger S‐cell fractions (> 10%) than diploid ones. High tumor ploidy correlated positively with high clinical stage (stage 1 versus stage > II) and with high histological grade but was unrelated to estrogen‐receptor content and menopausal status.