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MYCOPLASMA PNEUMONIAE ‐ STIMULATION OF LYMPHOCYTES OBTAINED FROM ADENOID VEGETATIONS AND BLOOD IN CHILDREN WITH AND WITHOUT SEROLOGICAL EVIDENCE OF MYCOPLASMA PNEUMONIAE INFECTION
Author(s) -
MOGENSEN HANS HENRIK,
MEISTRUPLARSEN KARENINGER,
RYDER LARS P.,
LIND KLAUS
Publication year - 1984
Publication title -
acta pathologica microbiologica scandinavica series c: immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0202
DOI - 10.1111/j.1699-0463.1984.tb00093.x
Subject(s) - mycoplasma pneumoniae , serology , mycoplasmataceae , mollicutes , adenoid , mycoplasma , microbiology and biotechnology , antigen , biology , immunology , virology , medicine , antibody , pneumonia
Thymidine incorporation in lymphocytes obtained from adenoids (AVL) and blood (PBL) and stimulated in vitro with Myoplasma (M.) pneumoniae antigen, was determined in 16 children with serological indication of a current or recent M.pneumoniae infection, and in 14 controls. Both AVL and PBL gave higher responses in the M.pneumoniae‐positive group than in the control group. The best discrimination between the two groups was achieved by AVL stimulated by M.pneumoniae at a high antigen concentration. Whilst PBL in the control group showed some responsiveness to M.pneumoniae, AVL did not respond, indicating that in this assay recent or actual M.pneumoniae infection is better expressed by AVL than by PBL.