Premium
THE CARDIAC ATRIOVENTRICULAR CONDUCTION SYSTEM IN FAMILIAL AMYLOIDOSIS WITH POLYNEUROPATHY
Author(s) -
Eriksson Anders,
Eriksson Peter,
Olofsson BertOve,
Thornell LarsEric
Publication year - 1983
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1983.tb02765.x
Subject(s) - amyloidosis , medicine , polyneuropathy , cardiology , electrical conduction system of the heart , amyloid polyneuropathy , pathogenesis , cardiac amyloidosis , conduction abnormalities , amyloid fibril , electrocardiography , disease , age of onset , amyloid β
Cardiac conduction disturbances are frequent in amyloidosis with cardiac involvement, but the pathogenesis of these electrocardiographic abnormalities is not clear. In the present study, the conduction systems in six patients with the Swedish variety of familial amyloidosis with polyneuropathy (FAP), have been analyzed. The results suggest that in FAP, direct amyloid infiltration of the atrioventricular conduction system accounts for the majority of the electrocardiographic disturbances.