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POLYMYXIN SUSCEPTIBILITY IN STAPHYLOCOCCI DIFFERENTIATING COAGULASE‐POSITIVE AND COAGULASE‐NEGATIVE STRAINS
Author(s) -
HELTBERG OLE,
BRUUN BRITA
Publication year - 1983
Publication title -
acta pathologica microbiologica scandinavica series b: microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0180
DOI - 10.1111/j.1699-0463.1983.tb00026.x
Subject(s) - coagulase , polymyxin , microbiology and biotechnology , polymyxin b , staphylococcus , biology , staphylococcus aureus , chemistry , bacteria , antibiotics , genetics
47 staphylococcal reference strains representing 13 species were tested for polymyxin sensitivity using tablet and disc diffusion methods. Corresponding MIC and IC 50 values were determined with a plate dilution assay. Coagulase‐positive strains were found to be more resistant towards polymyxin, and could thereby be separated from coagulase‐negative strains. Furthermore, 100 recently isolated staphylococci from clinical specimens were tested, and again the coagulase‐positive strains could be identified by their smaller tablet inhibition zones. We conclude that the polymyxin test is an aid in the fast differentiation of staphylococci in laboratories performing primary sensitivity tests.