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COAGULASE‐NEGATIVE STAPHYLOCOCCI AND CLOXACILLIN PROPHYLAXIS IN PACEMAKER SURGERY
Author(s) -
JACOBSON BENGT,
BLUHM GÖSTA,
JULANDER INGER,
NORD CARL ERIK
Publication year - 1983
Publication title -
acta pathologica microbiologica scandinavica series b: microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0180
DOI - 10.1111/j.1699-0463.1983.tb00016.x
Subject(s) - cloxacillin , coagulase , antibiotics , staphylococcus , medicine , microbiology and biotechnology , antibiotic prophylaxis , isolation (microbiology) , surgery , bacteria , staphylococcus aureus , biology , penicillin , genetics
In a prospective study of cloxacillin prophylaxis at pacemaker surgery per‐ and post‐operative cultures were made. The most commonly isolated organisms from the wound were coagulase‐negative staphylococci. These were typed by the scheme devised by Kloos and Schleifer. The routinely performed per‐operative culture was of very little prognostic value. However, the typing was found to be useful in cases with suspected infection, as repeated isolation of the same species of coagulase‐negative staphylococci with the same antibiotic susceptibility pattern may indicate pathogenicity. Incubation in enrichment medium for 2–4 days was needed in one patient who received antibiotic therapy when the specimen for culture was taken. The antibiotic prophylaxis did not eradicate even susceptible bacteria from the wound, but the infection rate was significantly lower in the prophylaxis group.