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MONOCYTE FUNCTIONS IN DIABETES MELLITUS
Author(s) -
Geisler Carsten,
Almdal Thomas,
Bennedsen JØRgen,
Rhodes Joan M.,
KØLendorf Klaus
Publication year - 1982
Publication title -
acta pathologica microbiologica scandinavica series c: immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0202
DOI - 10.1111/j.1699-0463.1982.tb01414.x
Subject(s) - phagocytosis , diabetes mellitus , monocyte , candida albicans , pinocytosis , concomitant , immunology , medicine , chemotaxis , endocrinology , chemistry , biology , microbiology and biotechnology , endocytosis , receptor
The aim of this study was to investigate the functions of monocytes obtained from 14 patients with diabetes mellitus (DM) compared with those of monocytes from healthy individuals. It was found that the total number of circulating monocytes in the 14 diabetic patients was lower than that from the healthy individuals. Phagocytosis of Candida albicans was decreased in the monocytes from the patients, whereas pinocytosis of acridine and phagocytosis of latex and sheep red blood cells were normal. The chemotactic response towards casein was enhanced. The possible consequences of these findings for the elucidation of concomitant infections in diabetic patients are discussed.