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FACTOR VIII RELATED ANTIGEN AND MAST CELLS
Author(s) -
KINDBLOM LARSGUNNAR
Publication year - 1982
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1982.tb00119_90a.x
Subject(s) - immunoperoxidase , mast (botany) , antigen , connective tissue , immunology , pathology , mast cell , biology , antibody , medicine , monoclonal antibody
Using an immunoperoxidase technique for the demonstration of factor VIII related antigen, a hitherto undescribed observation was made that human mast cells are positively stained for this coagulation factor. Mast cells of both connective tissue and mucosa origin were positively stained. The observation is considered to support the opinion that mast cells may play a role in local haemostasis.