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THE ANTRAL GASTRIN‐PRODUCING CELLS AND TISSUE GASTRIN IN DUODENAL ULCER PATIENTS
Author(s) -
NIELSEN H. OVERGAARD,
HAGE E.,
CHRISTIANSEN L. A.
Publication year - 1982
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1982.tb00117_90a.x
Subject(s) - gastrin , antrum , g cell , medicine , radioimmunoassay , endocrinology , secretion , gastric acid , chemistry , biology , stomach
Morphometric estimation of the antral G‐cells, radioimmunoassay estimation of the antral tissue gastrin, estimation of the antral mucosal volume and gastric acid secretion have been carried out on 10 duodenal ulcer patients. The total antral tissue gastrin varied from 52.4 to 245.1 μg and the mean G‐cell gastrin from 0.5 to 1.8 pg. No constant relationship was found between G‐cell densities and antral gastrin concentration, suggesting that no constant relationship exists between G‐cell numbers and G‐cell function. Furthermore, no constant relationship was observed between total antral gastrin and acid secretion.