Premium
THE HISTOLOGICAL CLASSIFICATION OF EARLY GASTRIC CANCER (MICRO‐INVASIVE CARCINOMA OF THE STOMACH)
Author(s) -
RUBIO C. A.,
SLEZAK P.,
ÖHMAN U.,
EMÅS S.
Publication year - 1982
Publication title -
acta pathologica microbiologica scandinavica series a :pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0108-0164
DOI - 10.1111/j.1699-0463.1982.tb00099_90a.x
Subject(s) - medicine , malignancy , stomach , gastric carcinoma , cancer , gastrectomy , carcinoma , pathology , gastroenterology , peptic , peptic ulcer
During a 3.5‐year period, January 1976 to June 1979, eleven cases of micro‐invasive carcinoma of the stomach (early gastric cancer) were detected in 45 gastrectomy specimens having a pre‐operative diagnosis of gastric carcinoma. The histological types found in the surgical specimens were highly differentiated (1), moderately differentiated (4), poorly differentiated (3) adenocarcinomas, one specimen had undifferentiated carcinoma, and in the remaining two cases mixed types were found. Multiple lesions were present in five spcimens. In ten of the eleven specimens, focal cystic dilatation of the deeper part of the gastric glands were found in areas overlapped by micro‐invasive carcinoma and/or in areas overlapped by mucosa showing chronic inflammation. The frequency of cystic dilatation of the gastric gland was much lower in specimens from patients with gastric or duodenal peptic ulcers. Thus, focal cystic dilatation present in negative gastric biopsies should be reported, thereby alerting the referring physician as to the possibility of a gastric malignancy.