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THE ANTRAL GASTRIN‐PRODUCING CELLS IN DUODENAL ULCER PATIENTS
Author(s) -
NIELSEN H. OVERGAARD,
LAURITSEN K.,
CHRISTIANSEN L. A.
Publication year - 1981
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1981.tb00223.x
Subject(s) - duodenal bulb , gastrin , antrum , medicine , parietal cell , gastroenterology , duodenal ulcer , pentagastrin , basal (medicine) , gastric acid , duodenum , pyloric antrum , g cell , endocrinology , secretion , stomach , insulin
Examination of the antral G‐cell density, acid secretion and fasting levels of serum‐gastrin were carried out on 20 patients with prepyloric ulcer (within 2 cm of the pyloric ring) and 76 patients with duodenal bulb ulcer. No difference was found in respect to the G‐cell density between the group of prepyloric and that with duodenal bulb ulcer, although a lower pentagastrin stimulated acid output and consequently a smaller parietal cell mass appeared to be present in the first group as compared to the second. No relationship was found in either group between fasting levels of serum‐gastrin and G‐cell density, suggesting that no constant relationship exists between G‐cell density and activity under basal conditions. A positive relationship, although statistically insignificant (0.05