Premium
INTERACTION OF FELINE SARCOMA VIRUS (FeSV) AND MYCOPLASMA
Author(s) -
LARSSON ERIK,
WESTERMARK BENGT,
PONTÉN JAN
Publication year - 1981
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1981.tb00211.x
Subject(s) - mycoplasma , virology , biology , antiserum , cell culture , embryo , virus , strain (injury) , microbiology and biotechnology , immunology , antibody , genetics , anatomy
A factor present in the supernatant of an established human glioma cell line U‐251 MG strongly suppresses feline sarcoma virus (FeSV) focus forming activity on feline embryo fibroblasts. The factor was identified as mycoplasma arginini. The enriched mycoplasma fraction had no cytpathogenic effect on the glioma cells or on the embryonic feline indicator cells. An antiserum prepared against this strain of mycoplasma abolished the inhibition. The exact mechanism is not known but arginine depletion in the medium seems to be an important factor.