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LOSS OF ENDOTOXIN LIBERATION IN NEISSERIA MENINGITIDIS
Author(s) -
ANDERSEN BJØRG MARIT,
SKJØRTEN FREDRIK,
SOLBERG OTTO
Publication year - 1981
Publication title -
acta pathologica microbiologica scandinavica section b microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-131X
DOI - 10.1111/j.1699-0463.1981.tb00188_89b.x
Subject(s) - neisseria meningitidis , microbiology and biotechnology , liberation , serial passage , agar plate , agar , cell wall , neisseria , bacteria , neisseriaceae , biology , chemistry , cell culture , antibiotics , biochemistry , in vitro , genetics
Four strains of Neisseria meningitidis were studied during serial passage. Upon subcultivation, two of them lost the ability to liberate endotoxin. Ultrastructurally, the two parent endotoxin liberating strains exhibited quantitively more free cell wall membranes and blebs in the medium than their non‐liberating variants. Similarly, the endotoxin‐releasing original strains exhibited higher sulfonamide resistance than their variants, and had markedly more sticky cells, which showed pronounced adherence to the surfaces of plastic and heated blood agar.