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ANTIBIOTIC SENSITIVITY PATTERN OF RECENT CLINICAL ISOLATES OF STREPTOCOCCUS PNEUMONIAE
Author(s) -
ZACKRISSON GUNILLA,
BRORSON JOHNERIK
Publication year - 1981
Publication title -
acta pathologica microbiologica scandinavica section b microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-131X
DOI - 10.1111/j.1699-0463.1981.tb00147_89b.x
Subject(s) - microgram , microbiology and biotechnology , chloramphenicol , streptococcus pneumoniae , ampicillin , penicillin , antibiotics , erythromycin , chemistry , antimicrobial , broth microdilution , in vitro , biology , minimum inhibitory concentration , biochemistry
Antimicrobial susceptibility of 180 recent isolates of Streptococcus pneumoniae was determined by microdilution technic. There was a high degree of susceptibility to both penicillin G and cefuroxime, except for one strain which required 0.25 μg/ml. All strains were inhibited by 0.06 μg/ml of ampicillin, clindamycin and erythromycin. When tested against doxycycline 97.2% of the strains were inhibited by 1.0 μg/ml. 8 μg/ml inhibited all strains. Three of the strains were chloramphenicol‐resistant with MIC more than 8 μg/ml. These strains could be shown to inactivate chloramphenicol. All strains but three were susceptible to 20/1 μg/ml of sulfamethoxazole/trimethoprim.