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MYCOPLASMA PNEUMONIAE ANTIGENS DEMONSTRATED BY CROSSED IMMUNOELECTROPHORESIS
Author(s) -
SCHÜTTEN HANS JØRGEN,
MOGENSEN HANS HENRIK,
LIND KLAUS
Publication year - 1980
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1980.tb00086.x
Subject(s) - mycoplasma pneumoniae , antigen , mycoplasma , complement fixation test , microbiology and biotechnology , immunoelectrophoresis , biology , virology , antibody , mollicutes , immune system , immunology , serology , medicine , pneumonia
Soluble Mycoplasma pneumoniae antigens were analysed by crossed immunoelectrophoresis. At least 15 precipitation arcs were developed between the soluble antigens and rabbit anti‐ Mycoplasma pneumoniae hyperimmune sera. Sera from Mycoplasma pneumoniae infected patients formed precipitation arcs which were identified with those formed by a chloroform‐methanol extract of Mycoplasma pneumoniae. Low concentrations of human antibodies, not detectable in a complement fixation test, were found to react with these antigens. The antigens were shown to cross‐react with antigens of Mycoplasma neurolyticum. Emphasis was placed on the technical development of the crossed immunoelectrophoresis for the analysis of immune‐precipitable antigens of Mycoplasma pneumoniae.