Premium
Cross‐Reactions Between Haemophilus Influenzae and Nineteen Other Bacterial Species
Author(s) -
SchiØtz P. O.,
HØiby N.,
Hertz J. B.
Publication year - 1979
Publication title -
acta pathologica microbiologica scandinavica section b microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-131X
DOI - 10.1111/j.1699-0463.1979.tb02448.x
Subject(s) - haemophilus influenzae , microbiology and biotechnology , antigen , haemophilus , antiserum , bacteria , chemistry , biology , virology , immunology , antibiotics , genetics
Forty‐one different antigens were demonstrated in an antigen preparation obtained by sonication of a Haemophilus influenzae (H. influenzae) type b strain, using crossed immunoelectrophoresis and antiserum obtained from rabbits. Antigens were characterized by absorption experiments with whole heat‐killed bacteria, temperature resistance and protein and polysaccharide staining. Cross‐reactions between H. influenzae type b and 19 other bacterial species were studied by various quantitative immunoelectrophoretic methods, using the reference system. A non‐capsulated H. influenzae cross‐reacted extensively (41 antigens) with H. influenzae type b and Haemophilus parainfluenzae , and Haemophilus haemolyticus showed considerable cross‐reactivity with H. influenzae type b (26 and 32 antigens respectively), while antigens from eight other bacterial species cross‐reacted to varying degrees with one to five H. influenzae antigens.