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ULTRASTRUCTURE OF LIPOGRANULOMAS IN HUMAN FATTY LIVER
Author(s) -
PETERSEN P.,
CHRISTOFFERSEN P.
Publication year - 1979
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1979.tb00022.x
Subject(s) - ultrastructure , histiocyte , fatty liver , lipid droplet , electron microscope , cell , human liver , pathology , liver cell , chemistry , cell membrane , biology , microbiology and biotechnology , medicine , biochemistry , disease , physics , optics , enzyme
Lipogranulomas from severe fatty livers due to alcoholism, diabetes or overweight were examined in the electron microscope. When a fat droplet protrudes through the cell membrane of a liver cell histiocytes and lymphocytes settle around it, and a lipogranuloma is formed. Remnants of the liver cell may be seen between the fat droplet and the histiocytes. It is confirmed that the fat droplets are situated extracellularly in the fully developed lipogranulomas.