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Feσ RECEPTORS IN HUMAN CHOROID PLEXUS
Author(s) -
Nyland Harald,
Matre Roald
Publication year - 1978
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1978.tb02571.x
Subject(s) - choroid plexus , receptor , cerebrospinal fluid , chemistry , antibody , immunoglobulin g , endocrinology , medicine , microbiology and biotechnology , biology , biochemistry , immunology , central nervous system
Cryostat sections of human choroid plexus adsorbed erythrocytes sensitized with IgG antibodies of human and rabbit origin. No adsorption occurred when the erythrocytes were sensitized with F(ab') 2 or Facb fragments. The reaction was strongly inhibited by intact IgG and by Fc fragments and not inhibited by Facb and F(ab') 2 or albumin. These properties are similar to those of corresponding receptors in human placenta. The presence of an Fey receptor in choroid plexus may be of significance for the transfer of IgG from blood to cerebrospinal fluid.