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Clinical Relevance of Histological Grading of Cancer of the Larynx
Author(s) -
HelwegLarsen Karin,
Græm Niels,
MeistrupLarsen KarenInger,
MeistrupLarsen Uggi
Publication year - 1978
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1978.tb02076.x
Subject(s) - larynx , grading (engineering) , malignancy , medicine , reproducibility , clinical significance , cancer , laryngeal neoplasm , radiology , pathology , surgery , statistics , biology , mathematics , ecology
Primary biopsies from 52 patients with cancer of the larynx were examined by two pathologists working independently. The malignancy of each case was graded twice with an interval of 1–1 1/2 month according to a histological scoring system elaborated by Jacobsson. The reproducibility of the system was found poor for individual prognostic purposes and no connection between histological grade and clinical course was demonstrated.