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Post‐Streptococcal Glomerulonephritis
Author(s) -
Ludwigsen Erik,
SØrensen Finn Hanberg
Publication year - 1978
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1978.tb02050.x
Subject(s) - glomerulonephritis , proteinuria , medicine , mesangial proliferative glomerulonephritis , acute glomerulonephritis , pathology , renal biopsy , biopsy , kidney
A light microscopical, quantitative glomerular examination was performed on renal biopsies from 14 patients with acute post‐streptococcal glomerulonephritis. A significant increase of 58% (p < 0.0025) in the total number of glomerular cells was found which was mainly due to an increase of endothelial cells (97%). Mesangial cells were, however, also increased (61 %) and mesangial area was increased by 34% (p < 0.05). Biopsies from patients with persisting proteinuria and/or hematuria revealed slight hypercellularity and an increase in mesangial area during the first six months of disease. The abnormalities in the acute phase of the disease could be so slight that they only would be disclosed by a quantitative investigation.