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Is Sulphated Blood‐Group Substance in Pancreas a Factor in Cystic Fibrosis?
Author(s) -
Rö;lla Gunnar,
Melsen Birte,
Sö;nju Torleif
Publication year - 1978
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1978.tb02016.x
Subject(s) - cystic fibrosis , medicine , pancreas , substance p , group (periodic table) , gastroenterology , chemistry , neuropeptide , receptor , organic chemistry
The present study showed that the pancreas of two monkey species contained sulphated blood‐group substance. Such strongly anionic molecules are known to bind calcium, and their solutions form gels in the presence of cations. It is suggested that such a mechanism may be involved in cystic fibrosis.