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IN VITRO SENSITIVITY OF TRICHOMONAS VAGINALIS AND CANDIDA ALBICANS TO CHEMOTHERAPEUTIC AGENTS
Author(s) -
LÖVGREN TIMO,
SALMELA ILKKA
Publication year - 1978
Publication title -
acta pathologica microbiologica scandinavica section b microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-131X
DOI - 10.1111/j.1699-0463.1978.tb00025.x
Subject(s) - clotrimazole , tinidazole , trichomonas vaginalis , nystatin , natamycin , candida albicans , trichomoniasis , microbiology and biotechnology , metronidazole , vaginitis , in vitro , corpus albicans , biology , antibiotics , medicine , antifungal , gynecology , biochemistry , genetics , food science
Strains of fresh clinical isolates of Trichomonas vaginalis and Candida albicans have been tested in vitro for their sensitivity to eight drugs used in the therapy of monilial and trichomonal vaginitis. Three of the chemotherapeutic agents, chlorchinaldol, clotrimazole and broxyquinoline, were effective against both organisms. Tinidazole and metronidazole were active against T. vaginalis. The strains of C. albicans were also sensitive to trichomycin, natamycin and nystatin. Tinidazole was the most effective trichomonacide, clotrimazole and chlorchinaldol were most effective against C. albicans , while chlorchinaldol had the best in vitro effect against both organisms. The ranges of the MICs are compared to values previously reported.