Premium
AGGLUTININS TO RABBIT ERYTHROCYTES IN EXTRACTS OF HUMAN MALIGNANT TISSUES
Author(s) -
Wesenberg Finn,
Tonder Olav
Publication year - 1977
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1977.tb03658.x
Subject(s) - agglutination (biology) , antibody , rabbit (cipher) , immunization , hemagglutination , biology , extracellular , microbiology and biotechnology , chemistry , immunology , biochemistry , statistics , mathematics
Agglutinins to rabbit erythrocytes in extracts from human malignant tissues were identified as the naturally occurring IgG antibodies in human serum to rabbit erythrocytes. This was revealed by agglutination, absorption, antiglobulin and inhibition tests, immunization of rabbits and immunochemical analyses. The agglutinins can therefore be used as convenient markers for both extracellular immunoglobulin and unspecifically bound immunogobulin in tumour tissues. Apparently the extracts also contained small amounts of IgA antibodies to rabbit erythrocytes.