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THERMOSTABLE NEISSERIA GONORRHOEAE ANTIGENS EXAMINED BY A BACTERIAL AGGLUTINATION TEST
Author(s) -
Angelsen Guri Eggset,
Mæland Johan
Publication year - 1977
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1977.tb03646.x
Subject(s) - neisseria gonorrhoeae , microbiology and biotechnology , neisseria , antigen , agglutination (biology) , biology , latex fixation test , direct agglutination test , bacteria , antibody , immunology , genetics , serology
Rabbit antisera against three different N. gonorrhoeae isolates agglutinated heated gonococci (1007°C, 2 h) before and after treatment with periodate or pronase, but this was not the case with gonococci exposed to the combined action of the reagents. All agglutinins could be removed by absorption of antiserum with untreated or heat‐treated gonococci or with a heat extract of the bacteria. Antiserum absorbed with the lipopolysaccharide still agglutinated the heated gonococci both before and after exposure of the bacteria to periodate or pronase. The results of cross‐absorption experiments indicated strain variation of thermostable antigenic determinants involved in the agglutination reaction.