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IN VITRO STUDIES ON NORMAL, STIMULATED AND IMMUNOLOGICALLY ACTIVATED MOUSE MACROPHAGES
Author(s) -
Bennedsen J.,
Riisgaard S.,
Rhodes J. M.,
Larsen S. Olesen
Publication year - 1977
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1977.tb03638.x
Subject(s) - in vitro , microbiology and biotechnology , chemistry , biology , immunology , biochemistry
The intracellular generation time of Listeria monocytogenes is increased in monolayers of PE macrophages from mice immunized with BCG, listeria and T.A.B. vaccine as compared with monolayers of PE macrophages from normal mice stimulated intraperitoneally with proteose‐peptone. Thus non‐specifically stimulated and immunologically activated macrophages, although sharing several other characteristics, differ in their capacity to control intracellular bacterial infection.