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PSEUDOMONAS AERUGINOSA INFECTION IN CYSTIC FIBROSIS:
Author(s) -
HØiby Niels
Publication year - 1977
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1977.tb03624.x
Subject(s) - precipitin , immunoelectrophoresis , antigen , pseudomonas aeruginosa , cystic fibrosis , chemistry , medicine , microbiology and biotechnology , immunology , biology , bacteria , genetics
Sera from 119 patients with cystic fibrosis were examined for precipitating antibodies against anodic migrating P. aeruginosa antigens by means of crossed Immunoelectrophoresis. The presence of precipitins against cathodic migrating P. aeruginosa antigens was investigated by means of classical Immunoelectrophoresis. Thirty‐six per cent of the sera contained precipitins against both anodic and cathodic antigens, 20 per cent contained only precipitins against anodic antigens, none contained only precipitins against cathodic antigens, and 44 per cent had no demonstrable P. aeruginosa precipitins. The amount of extra information obtained by combining the results of classical immunoelectrophoresis with the results of crossed immunoelectrophoresis was small.