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AN INDIRECT HAEMAGGLUTINATION TEST FOR DEMONSTRATION OF GONOCOCCAL ANTIBODIES USING GONOCOCCAL PILI AS ANTIGEN:
Author(s) -
Reimann Karin,
Lind Inga
Publication year - 1977
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1977.tb03620.x
Subject(s) - complement fixation test , hemagglutination , pilus , antibody , antigen , medicine , gonococcal infection , microbiology and biotechnology , immunology , virology , biology , serology , syphilis , sexually transmitted disease , escherichia coli , biochemistry , gene , human immunodeficiency virus (hiv)
An indirect haemagglutination (IHA) test for detection of gonococcal antibodies in human sera was established using purified pili as antigen. The majority of sera (44/51), positive in the gonococcal complement fixation test, were also positive in the IHA test with titres within the range 320–10,000. The results obtained for the following three groups of sera indicate a comparatively high specificity of the IHA test: 1) 52 sera from children below 12 years of age were all negative, 2) 98 per cent (184/188) of sera from blood donors were negative, 3) only sera from three adults out of 21 patients with meningococcal infections gave a positive reaction.