Premium
INCREASED PERMEABILITY FOR PLASMA COMPONENTS OF THE CEREBRAL VESSELS DURING ACUTE ANGIOTENSIN HYPERTENSION IN RATS
Author(s) -
Olsen Finn
Publication year - 1977
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1977.tb00448.x
Subject(s) - permeability (electromagnetism) , angiotensin ii , medicine , vascular permeability , cardiology , chemistry , blood pressure , membrane , biochemistry
Experimentally induced acute angiotensin hypertension has been shown to increase the permeability of cerebral arterioles, venules and veins to plasma components within a few hours. This increase in permeability was demonstrated by means of circulating homologous fluorescent serum proteins and colloidal carbon particles. The results support the view that an increased permeability of the cerebral vessels to plasma components is either a causal or an additional pathogenetic factor in the development of the hypertensive encephalopathy.