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AGE‐ AND SEX‐RELATED DISTRIBUTION OF ANTIBODIES TO HEPATITIS B SURFACE AND CORE ANTIGENS IN A SWEDISH POPULATION
Author(s) -
Hansson Bengt Göran
Publication year - 1976
Publication title -
acta pathologica microbiologica scandinavica section b microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-131X
DOI - 10.1111/j.1699-0463.1976.tb01951.x
Subject(s) - radioimmunoassay , antibody , antigen , hemagglutination , population , hepatitis b , medicine , immunology , distribution (mathematics) , virology , mathematical analysis , mathematics , environmental health
Serum samples from people born between the years 1895 and 1970 were collected and tested for antibody to hepatitis B surface antigen (anti‐HB s ) by passive haemagglutination (PHA) and radioimmunoassay (RIA), and for antibody to hepatitis B core antigen (anti‐HB c ) by immunoelectroosmophoresis (IEOP). Neither anti‐HB s nor anti‐HB c was detected in the serum from anyone under 15 years of age. The prevalence of anti‐HB s and anti‐HB c showed peaks of 9.2 and 8.3 per cent, respectively, in the age group of 40–49 years. The distribution of antibody was equal between men and women. Eighty per cent of the sera with anti‐HB s were also positive for anti‐HB c . All sera positive for anti‐HB c also contained anti‐HB s .