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GENETIC MAPPING OF THE K1 AND K4 ANTIGENS (L) OF ESCHERICHIA COLI
Author(s) -
Ørskov Ida,
Sharma Virendra,
Ørskov Frits
Publication year - 1976
Publication title -
acta pathologica microbiologica scandinavica section b microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-131X
DOI - 10.1111/j.1699-0463.1976.tb01914.x
Subject(s) - antigen , escherichia coli , biology , gene , locus (genetics) , genetics , strain (injury) , microbiology and biotechnology , anatomy
Escherichia donor strains having antigen K1(L) or K4(L) transfer these K antigens to recipient cells at a genetic locus ( kps A ) similar to that of K10(L) and K54(L) linked to ser A. In crosses between the K10 donor strain and recipient strains O8:K8(L), O8:K27(A) and O9:K57(B) all recombinants which inherit donor K antigen also inherit K antigen of recipient. This result is interpreted as non‐allelism between donor and recipient K antigens, and it is assumed that the structure of all polysaccharide K antigens of strains having O antigens O8 or O9, whether termed L, A, or B, are controlled by genes which differ in their location on the chromosome from genes controlling polysaccharide K antigens associated with most other O antigens.