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MULTIPLICATION OF MYCOBACTERIUM TUBERCULOSIS AND MYCOBACTERIUM BOVIS IN MICROTUS AGRESTIS (FIELD VOLE)
Author(s) -
Jespersen Andr.
Publication year - 1976
Publication title -
acta pathologica microbiologica scandinavica section b microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-131X
DOI - 10.1111/j.1699-0463.1976.tb01901.x
Subject(s) - mycobacterium bovis , microtus , tuberculosis , mycobacterium tuberculosis , biology , microbiology and biotechnology , vole , veterinary medicine , medicine , pathology , zoology , population , environmental health
The multiplication of bacteria is examined by quantitative culture from the organs of two groups of field voles injected intraperitoneally with a large dose of M. tuberculosis or a small dose of M. bovis and killed at intervals during a period of up to 3 months after the injection. M. tuberculosis given in a dose of 7 times 10 5 viable units did not multiply, or multiplied only to a small extent. None of the animals in the group died from tuberculosis and the macroscopical lesions found at autopsy were insignificant. In contrast, a dose of 14 viable units of M. bovis provoked generalized tuberculosis running a rapid, fatal course. The bacteria multiplied almost uninhibited throughout the course of the infection.