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METHICILLIN‐INDUCED NEPHROPATHY.
Author(s) -
Hansen Erik Sommer,
Tauris Palle
Publication year - 1976
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1976.tb00139.x
Subject(s) - nephropathy , nephritis , immunofluorescence , staining , basement membrane , indirect immunofluorescence , staphylococcus aureus , immunology , medicine , pathology , interstitial nephritis , antibody , microbiology and biotechnology , chemistry , biology , kidney , bacteria , endocrinology , genetics , diabetes mellitus
A case is reported of methicillin‐induced acute interstitial lymphocytic nephritis following treatment of a Staphylococcus aureus infection. Direct immunofluorescence showed a linear staining of the tubular basement membrane with anti‐IgG and ‐C3. It is suggested that both cellular and humoral immunologic mechanisms are of pathogenic importance.