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HEALING OF A CRUSH INJURY IN RAT STRIATED MUSCLE:
Author(s) -
Järvinen Markku
Publication year - 1976
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1976.tb00114.x
Subject(s) - crush injury , medicine , sprouting , mobilization , anatomy , angiography , vascular smooth muscle , surgery , biology , smooth muscle , history , botany , archaeology
Vascular ingrowth into the injured area of a partially crushed gastrocnemius muscle was studied by micro‐angiography 2 to 14 days after the trauma in 40 rats treated by mobilization or immobilization. In mobilized muscles, the sprouting of new capillaries occurred more rapidly and intensively than in injured muscles treated by immobilization. The sequence of events was found to be slightly delayed if mobilization was started after immobilization for two days. The speed and intensity of tissue repair, as studied histologically, was directly correlated with vascular ingrowth, especially during the first week.