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CONGENITAL GENERALIZED LIPODYSTROPHY:
Author(s) -
Berge Thorbjörn,
Brun Arne,
Hansing Bengt,
Kjellman Bengt
Publication year - 1976
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1976.tb00109.x
Subject(s) - lipodystrophy , medicine , pediatrics , dermatology , immunology , human immunodeficiency virus (hiv) , viral load , antiretroviral therapy
Generalized lipodystrophy (Berardinelli‐Seip's syndrome) was diagnosed in a boy at the age of 81/2 months. Ten months later he died because of aspiration of food. Necropsy with special reference to the CNS revealed hypothalamic lesions, probably of a malformative or hamartomatous nature. The findings lend additional support to the view that hypothalamic dysfunction is responsible for the signs and symptoms of generalized lipodystrophy.