Premium
LYMPHOCYTE MARKERS IN NEWBORN INFANTS
Author(s) -
HALLBERG T.,
HALLBERG ANITA
Publication year - 1976
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1976.tb00058.x
Subject(s) - peripheral blood , lymphocyte , immunology , medicine , antibody , andrology
Purified peripheral blood lymphocytes from 20 newborn infants and 12 adults have been studied for the presence of surface markers. Adults and infants did not differ in the percentage of sheep RBC‐binding cells (means 58‐65 per cent) or in Ig‐bearing cells measured by the mixed antiglobulin reaction (means 7.2‐11.6 per cent). However, newborn infants had a significantly lower percentage of lymphocytes binding Fc of IgG (mean 10.4 per cent) as compared to adults (mean 17.2 per cent). No overall correlation between plasma Ig levels and Ig‐bearing lymphocytes was found but a single infant with increased plasma IgA also showed the highest level of Ig‐bearing lymphocytes among all infants.