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CROSS‐REACTIONS OF KLEBSIELLA
Author(s) -
Heidelberger Michael,
Nimmich Wolfgang,
Eriksen Jorunn,
Dutton Guy G. S.,
Stirm Stephan,
Fang Chyang T.
Publication year - 1975
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1975.tb01657.x
Subject(s) - klebsiella , polysaccharide , klebsiella pneumoniae , microbiology and biotechnology , chemistry , biology , biochemistry , escherichia coli , gene
An earlier study of more than 60 Klebsiella K‐polysaccharides in anti‐pneumococcal sera of many capsular types provided the impetus for the present work. With anti‐ Klebsiella sera, some of these cross‐reactions are now shown to be reciprocal. In most instances in which several or many K‐substances precipitated antipneumococcal sera of a given type, these same K‐polysaccharides were cross‐reactive with one or more anti‐ Klebsiella sera belonging to the same group. For example, the polysaccharides K1, 15, 24, 31, 39, 42, and 59 precipitated an equine antipneumococcal type X serum. Pneumococcal capsular polysaccharide type X and Klebsiella polysaccharides K15, 24, 31, 39, 42, and 59 precipitated one or both of the equine anti‐ Klebsiella K1 sera available. Similar results with anti‐ Klebsiella rabbit sera to other K‐types show the validity of this approach in revealing hitherto unknown serological, and hence chemical, relationships between the K‐types.