Premium
DELAYED HYPERSENSITIVITY TO STAPHYLOCOCCAL PROTEIN A DETECTED BY LEUCOCYTE MIGRATION INHIBITION
Author(s) -
Helgeland Svein M.,
æss Ragnar R. N.,
Grov Arne
Publication year - 1975
Publication title -
acta pathologica microbiologica scandinavica section c immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0304-1328
DOI - 10.1111/j.1699-0463.1975.tb01603.x
Subject(s) - peptidoglycan , staphylococcus aureus , microbiology and biotechnology , protein a , delayed hypersensitivity , chemistry , staphylococcus , strain (injury) , staphylococcal infections , in vitro , immunology , bacteria , biology , antigen , cell wall , biochemistry , antibody , anatomy , genetics
Helgeland, S. M., Nsess, R. R. & Grov, A. Delayed hypersensitivity to staphylococcal protein A detected by leucocyte migration inhibition. Acta path, microbiol. scand. Sect. C, 83: 15–18, 1975. Delayed hypersensitivity to staphylococcal protein A was indicated by the migration inhibition reaction (MIR), using peritoneal cells from protein A sensitized guinea pigs. No cross‐reactivity between protein A, polysaccharide A and peptidoglycan was found. Peptidoglycan from Staphylococcus aureus strain Cowan 1 inhibited almost completely the migration of cells from both sensitized and unsensitized cells.