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THE EFFECT ON THE RAT LIVER OF LONG‐TERM ADMINISTRATION OF DIFFERENT ALCOHOLIC BEVERAGES TOGETHER WITH INADEQUATE DIETS
Author(s) -
Jordö Lars,
Olsson Rolf
Publication year - 1975
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1975.tb01402.x
Subject(s) - calorie , wine , medicine , vitamin , ethanol , alcoholic liver disease , cirrhosis , alcohol , physiology , endocrinology , food science , chemistry , biochemistry
Rats were given 36 per cent of calories as ethanol, gin, brandy, whisky or red wine together with hypocaloric (25 per cent of normal), hypocaloric—low‐protein—highfat, or hypocaloric—low vitamin diets for several months and compared with rats given isocaloric amounts of glucose instead of alcohol. In spite of high mortality rate no severe liver lesions occurred, especially no cirrhosis. Congeners present in different alcoholic beverages therefore seem to lack important hepatotoxic effects at least in the rat.