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LOCALISATION OF HUMAN α‐FOETOPROTEIN SYNTHESIS IN HEPATOBLASTOMA CELLS BY IMMUNOFLUORESCENCE AND IMMUNOPEROXIDASE METHODS
Author(s) -
NørgaardPedersen B.,
Dabelsteenn E.,
Edelingn C.J.
Publication year - 1974
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1974.tb03839.x
Subject(s) - hepatoblastoma , immunoperoxidase , immunofluorescence , immunoelectrophoresis , pathology , indirect immunofluorescence , hepatocyte , liver tissue , medicine , biology , antibody , immunology , monoclonal antibody , biochemistry , in vitro
By means of indirect immunofluorescence (IF) and indirect immunoperoxidase (IP) technique the presence of α‐foetoprotein (AFP) has been demonstrated in foetal liver tissue as well as in liver tissue from two cases of hepatoblastoma. In both cases of hepatoblastoma the serum AFP were determined by rocket immunoelectrophoresis. Removal of the tumours caused a rapid fall in the concentration of serum AFP.