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EFFECTS OF SUPPLY AND WITHDRAWAL OF FLUORIDE.
Author(s) -
Rosenquist B.
Publication year - 1974
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1974.tb03585.x
Subject(s) - fluoride , chemistry , magnesium , cortical bone , calcium , body weight , endocrinology , medicine , anatomy , inorganic chemistry , organic chemistry
The concentrations of fluoride, calcium, magnesium and phosphorus in cortical bone ash were determined on whole and microdissected fluorotic bone of growing rabbits. The animals were given 10 mg of F ‐ per kg body weight daily during 14 weeks. During this period, excessive periosteal bone formation occurred at the lateral part of the tibial middiaphysis. The newly formed bone contained more fluoride than the average experimental bone, but the data suggested a similar “fluoride pressure” on each part of the cortex. Thus the localization of the periosteal bone formation was not regarded due to differences in “fluoride pressure”. The magnesium concentration was higher in the experimental bone than in the control bone. However, any relationship between fluoride and magnesium concentrations was not observed.