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FAILURE TO DEMONSTRATE IMMUNOGLOBULIN E IN GLOMERULI OF PATIENTS WITH VARIOUS NEPHROPATHIES
Author(s) -
Bennich H.,
Bergquist N. R.,
Bergstrand A.,
Bergström J.,
Johansson S. G. O.,
Wasserman J.
Publication year - 1974
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1974.tb02318.x
Subject(s) - immunoglobulin e , antibody , amyloidosis , immunofluorescence , immunology , medicine , immunoglobulin m , immunoglobulin g , pathology
An immunofluorescence study of 119 kidney biopsies from a variety of renal affections, including transplants, is presented. The investigation was carried out with special reference to the possible presence of IgE, but simultaneously, other immunoglobulin classes (IgG, IgA, IgM) as well as complement (C 3) and fibronogen were sought for. Out of the 119 biopsies examined, 117 were negative if tested with a monospecific anti‐IgE conjugate. The only definitely positive finding of IgE came from two patients with amyloidosis.