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STRUCTURAL AND FUNCTIONAL PROPERTIES OF BLOOD MONOCYTES CULTURED IN VITRO
Author(s) -
ødegaard Arne,
Viken KarlErik,
Lamvik Jon
Publication year - 1974
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1974.tb02316.x
Subject(s) - petri dish , candida albicans , peripheral blood mononuclear cell , in vitro , microbiology and biotechnology , immunology , biology , cell , biochemistry
Mononuclear phagocytes from human venous blood were cultured in plastic Petri dishes and on glass coverslips in Petri dishes. After an initial cell loss, the cell cultures showed a good structural and functional stability. No signs of cell proliferation were noticed. Young cultured cells had an appearance like that of monocytes while older cultured cells appeared like macrophages with the ability to engulf and digest heat‐killed Candida albicans. The young cells showed the ability of engulfing Candida, but were unable to break down the engulfed corpuscles.