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6‐PHOSPHOGLUCONATE DEHYDROGENASE AND ENZYMES OF THE ENTNER‐DOUDOROFF PATHWAY IN NEISSERIA
Author(s) -
Holten Eirik
Publication year - 1974
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1974.tb02313.x
Subject(s) - dehydrogenase , aldolase a , enzyme , neisseria , phosphogluconate dehydrogenase , biochemistry , neisseria meningitidis , microbiology and biotechnology , biology , chemistry , bacteria , glucose 6 phosphate dehydrogenase , genetics
6‐phosphogluconate dehydrogenase, 6‐phosphogluconate dehydrase and 2‐keto‐3‐deoxy‐6‐phosphogluconate aldolase were studied in several Neisseria species. 6‐phosphogluconate dehydrogenase and 2‐keto‐3‐deoxy‐6‐phosphogluconate aldolase were present in all strains of “true neisserias”. The synthesis of 6‐phosphogluconate dehydrogenase was stimulated by glucose in the saccharolytic Neisseriae , and its activity was stimulated by NADP in N. meningitidis and N. gonorrhoeae. 6‐phosphogluconate dehydrase was present in most strains of “true neisserias”, except in N. cinerea and N. elongata. This enzyme was induced by glucose in the saccharolytic Neisseriae. In N. flavescens its synthesis was inhibited by glucose.