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CAPACITY OF GROUP A, B, C, D AND G STREPTOCOCCI TO AGGLUTINATE SENSITIZED SHEEP RED CELLS
Author(s) -
Christensen Poui.,
Kronvall Göran
Publication year - 1974
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1974.tb02287.x
Subject(s) - group a , agglutination (biology) , microbiology and biotechnology , trypsin , group b , streptococcus , serology , pepsin , antibody , streptococcus agalactiae , biology , streptococcus pyogenes , immunology , bacteria , enzyme , staphylococcus aureus , medicine , biochemistry , genetics
The reactivity of streptococci with sheep red cells, sensitized with a subagglutinating dose of rabbit anti‐sheep red cell antibodies was studied; agglutination of sensitized and not non‐sensitized sheep red cells by streptococci was demonstrated in isolates belonging to groups A, B, C, D and G. The frequencies of isolates which had the capacity to agglutinate were 97, 88 and 100 per cent in group A, C and G, but only 47 and 33 in group B and D. The agglutination of sensitized sheep red cells by streptococci diminished after treatment of the streptococci with protease from Streptomyces griseus , but was not affected by pepsin or trypsin treatment. Heating the streptococci at 60°C for 30 minutes and repeated subculturing did not suppress their agglutinating activity. Besides, various streptococcal extracts agglutinated sensitized sheep red cells. The presence of an immunoglobulin G reactivity in streptococci might cause certain difficulties in the serological grouping and typing of streptococci.