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STUDIES ON STACHYBOTRYS ALTERNANS
Author(s) -
Korpinen EevaLiisa,
Kurkinen M.,
Nummi M.,
Enari T.M.
Publication year - 1974
Publication title -
acta pathologica microbiologica scandinavica section b microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-5563
DOI - 10.1111/j.1699-0463.1974.tb02285.x
Subject(s) - toxin , chromatography , toxicity , chemistry , silica gel , resorcinol , solvent , fluorescence , microbiology and biotechnology , biochemistry , biology , organic chemistry , physics , quantum mechanics
Chromatographic analyses and tissue culture toxicity tests were simultaneously carried out with stachybotrys crude toxin. Toxic fractions were localized by tissue culture toxicity tests, and further chemical analyses were concentrated on these parts. By using consecutive partition chromatography on silica gel columns with different solvent systems the crude toxin was resolved into three components which were toxic to mouse primary fibroblast culture. These three toxic stachybotrys components contained some impurities, they were non‐fluorescent and they gave a negative resorcinol test.