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HISTOLOGICAL LIVER DISORDER AND ANTI‐COLON ANTIBODIES IN ULCERATIVE COLITIS
Author(s) -
Marcussen Henrik
Publication year - 1974
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1974.tb00397.x
Subject(s) - ulcerative colitis , medicine , histology , gastroenterology , pathology , antibody , incidence (geometry) , biopsy , liver biopsy , immunofluorescence , disease , immunology , physics , optics
In 97 patients with ulcerative colitis, representing a large clinical spectrum of the disease, liver disorder was assessed by estimation of percutaneous liver biopsy. Thirty‐nine patients presented histological changes—the greater part of minor degree—, i.e. an incidence of abnormal liver histology in ulcerative colitis in 40 per cent (95 per cent confidence limits 30–51 per cent). Antibodies against mucous‐containing cells of the colon epithelium, detected by the immunofluorescence technique and without correlation to histological liver disorder, were found in 19 patients.