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THE ADRENAL GLANDS OF ELDERLY MEN IN RELATION TO ABNORMAL PROSTATIC GROWTH
Author(s) -
Haugen Olav A.
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1973.tb03577.x
Subject(s) - histology , hyperplasia , autopsy , prostate , medicine , adrenal gland , endocrinology , pathology , physiology , cancer
The variability of adrenal weight and cortical thickness was studied in a consecutive autopsy series comprising 154 men over 40 years of age. Among several factors tested by multiple regression analysis, a significant and positive correlation between adrenal weight and body length was demonstrated only. At all age levels and within all groups of prostatic histology the adrenal weights varied markedly. No significant association between the adrenal parameters studied, including the presence of adreno‐cortical adenomas, and any of the defined groups of prostatic histology was found in this series. With advancing age, however, a significant decrease of adrenal weight appeared in men with prostatic carcinoma which was not seen in men with benign hyperplasia. The validity and importance of this observation is obscure. It is concluded on the basis of morphological studies of the adrenal glands that there is no firm indication to suggest that the adrenal glands are involved in the patho‐genesis of abnormal growth of the prostate in elderly men.