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EFFECTS OF SUPPLY AND WITHDRAWAL OF FLUORIDE Experimental Studies on Growing and Adult Rabbits 1, Concentration of Fluoride in Cortical Bone
Author(s) -
Rosenquist Jan
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1973.tb03553.x
Subject(s) - fluoride , chemistry , cortical bone , zoology , dentistry , endocrinology , medicine , inorganic chemistry , biology , anatomy
The fluoride content in cortical bone ash of growing rabbits given 0.5 and 10 mg of fluoride per kg weight per day was studied after 2, 4, 7 and 14 weeks. The retention was linear. The amount of fluoride in the diet, 2 p p m, was not sufficient to maintain the fluoride level in the control group in which there thus was a small decrease. After withdrawal of fluoride at practically completed growth (21 weeks) the fluoride content was determined after another 4, 12 and 24 weeks. There was no decrease in the fluoride content, suggesting that the fluoride was firmly bound to the bone minerals.