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THE ADRENAL GLANDS OF MICE WITH HEREDITARY PITUITARY DWARFISM
Author(s) -
Shire John G. M.,
Hambly Elizabeth A.
Publication year - 1973
Publication title -
acta pathologica microbiologica scandinavica section a pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0365-4184
DOI - 10.1111/j.1699-0463.1973.tb03528.x
Subject(s) - dwarfism , endocrinology , medicine , adrenal cortex , medulla , biology , cortex (anatomy) , gene , neuroscience , genetics
Histological studies were made of the adrenal glands of mice with hereditary pituitary dwarfism. No evidence was found for a deficiency of ACTH in these mice. Quantitative comparisons with their normal sibs showed that the permanent cortex was not disproportionately small in the dwarf mice. It was confirmed that the adrenal glands of dwarf mice lack an X zone. The medulla was found to be large, relative to the permanent cortex, in both male and female dwarfs.